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R&D Capabilities

The Group's biggest strength from an R&D perspective is the concentration of corporate resources into products that fight the two biggest skincare concerns of women―dark spots and wrinkles. Particular attention is directed toward basic research into the areas of anti-aging and skin-whitening and the development of new materials, and efforts have generated original ingredients, patents and other materials available onry to the Group. For example, POLA pioneered the world's first application of hyaluronic acid in cosmetics in the 1980s and brought these products to market. More recently, in 2017, POLA debuted the industry's first quasi-drug to improve wrinkles.
In addition, the skincare market is stable and has been for some time, according to past statistics. Efforts to refine skincare-oriented research and technology development capabilities underpin the competitiveness and excellence of each Group brand and fuel high rates of repeat purchases and enhanced profitability overall.

R&D Highlights

POLA CHEMICAL INDUSTRIES wins the Best Basic Research Award at IFSCC Congress

POLA CHEMICAL INDUSTRIES, INC. won the Best Basic Research Award at the 28th International Federation of Societies of Cosmetic Chemists (hereafter referred to as "IFSCC") Congress

Theme: "Antimicrobial peptide human beta defensin-3 (hBD-3) as a key factor for acne flare-up during the premenstrual stage"

There are many women who experience acne flare-up before menstruation. However, the mechanism behind the symptom has not been revealed and there are no proper treatment offered.
By focusing on female hormone called progesterone, which increases before menstruation and bactericidal peptide produced from epidermis, this research discovered the following:

1. Human beta-defensin-3 (hBD-3), one of the cutaneous bactericidal peptides, show antibacterial activity against Propionibacterium acne (P. acnes)s, the causative pathogen of acnes..

2. A female hormone called progesterone which increases before menstruation, reduce expression of hBD-3 in human epidermal cells.

Therefore, progesterone reduce expression of hBD-3 which has antibacterial activity against P. acnes, and this may be one of the causes for acne flare-up before menstruation. By applying this finding, more effective skincare products for acne treatment can be offered.

IFSCC is the most prestigious worldwide federation dedicated to international cooperation in cosmetic science. It holds a congress every 2 years where leading researchers in cosmetic science present their latest technologies. At the 28th Congress, there were 78 entries for oral presentation and 464 entries for poster presentation. Among these presentations, the above-mentioned research won the Best Basic Research Award. POLA CHEMICAL INDUSTRIES received the award 8 times at the congress.

POLA ORBIS HOLDINGS will continue its efforts to research the leading-edge technology in cosmetics to develop high-value-added products that are infused with the Group's original ingredients.

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